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FIGURE 1: Positions of Centromeres, Regions of Excess IBD, HLA Region, and SNP-Poor Regions (Build 36)
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FIGURE 2: Positions of Centromeres, Regions of Excess IBD, HLA Region, and SNP-Poor Regions (Build 37)
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I do a lot of chromosome mapping using Kitty Cooper's great Ancestor Mapping Tool. There are a few regions in the genome more likely to have issues when comparing matching DNA segments with others: at the centromeres and regions of excess IBD sharing (IBD = identical by descent). Instead of looking these up in tables, I've plotted them on chromosome maps, as visual representations are easier than looking up values in a table and they allow side-by-side comparisons to be made to my chromosome maps. I also added the Human Leukocyte Antigen (HLA) region on chromosome 6, which exhibits greater IBD sharing than expected, and the SNP-poor regions (SNP = single nucleotide polypeptide) rather than having blank areas on the chromosome map.
